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Saturday, April 18, 2020 | History

6 edition of Superantigens (Current Topics in Microbiology & Immunology) found in the catalog.

Superantigens (Current Topics in Microbiology & Immunology)

Bernhard Fleischer

Superantigens (Current Topics in Microbiology & Immunology)

  • 317 Want to read
  • 12 Currently reading

Published by Springer .
Written in English

    Subjects:
  • General,
  • Antigens,
  • Medical / Nursing,
  • Science/Mathematics

  • The Physical Object
    FormatHardcover
    Number of Pages137
    ID Numbers
    Open LibraryOL10153499M
    ISBN 100387542051
    ISBN 109780387542058


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Superantigens (Current Topics in Microbiology & Immunology) by Bernhard Fleischer Download PDF EPUB FB2

Discusses the potential for the use of superantigens in bioterrorism. Serves as essential reading for researchers in the fields of microbiology, immunology, biotechnology, molecular medicine, and clinical infectious : Hardcover. Containing practical examples combining basic science and clinical research, Superantigens explores mammary tumor virus (MMTV) transmission compiles new data on the role of superantigens in human immunodeficiency virus, cytomegalovirus, rabies virus, and Epstein-Barr virus details the biophysical and biological properties of staphylococcal and streptococcal toxins elaborates on the role of Cited by: Superantigens: A Pathogen's View of the Immune System (CURRENT COMMUNICATIONS IN CELL AND MOLECULAR BIOLOGY): Medicine & Health Science Books @ hor: Brigitte T.

Huber, Ed Palmer. Superantigens (Current Topics in Microbiology & Immunology) 1st Edition by B. Fleischer (Author), H. Sjorgen (Editor) ISBN ISBN Why is ISBN important. ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book.

Format: Hardcover. This volume combines protocols that encompass the true variety of investigation done on superantigens in the fields of microbiology, immunology, molecular biology, biochemistry, and cellular biology, with a Superantigens book focus on disease models utilized to determine the role of superantigens in human.

Superantigens is the first comprehensive examination of these fascinating proteins ever published. Organized into five sections and sixteen chapters, this volume provides an essential overview of many aspects of superantigen biology.

A team of internationally respected researchers covers the basic molecular mechanisms of superantigen action, their structure and function, and their role in.

Viral Superantigens presents a complete review Superantigens book this new area of study. Edited Superantigens book a leading researcher and authored by a distinguished team of contributors, this comprehensive analysis covers every aspect of viral superantigens and related subjects, including critical topics such as effects on the T cell repertoire and viral superantigen-mediated : Hardcover.

Viral Superantigens - CRC Press Book Since the discovery of viral superantigens inimmunologists have made a number of new discoveries.

The discoveries, especially those relating to the interplay between the immune Superantigens book and viruses producing superantigens, have had a great impact on immunology and virology, Superantigens book it appears that s.

Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger excessive stimulation of human and other mammalian T lymphocytes. This leads to a massive release of T cell mediators and pro-inflammatory cytokines contributing to diseases such Superantigens book toxic shock syndrome.

In contrast to conventional peptides, SAgs bind as unprocessed molecules to major Cited Superantigens book 8. Morten Soögaard, in Encyclopedia of Immunology (Second Edition), Superantigens (SAgs) are proteins produced by bacteria and Superantigens book that are able to stimulate a large proportion of T lymphocytes via interaction with the variable domain of the β chain of the T cell antigen receptor (TCR-Vβ).

Book Description. Since the discovery of viral superantigens inimmunologists have made a number of new discoveries. The discoveries, especially those relating to the interplay between the immune system and viruses producing superantigens, have had a great impact on immunology and virology, as it appears that some diseases are Superantigens book or exacerbated by viral superantigens.

About this book Introduction This volume combines protocols that Superantigens book the true variety of investigation done on Superantigens book in the fields of microbiology, Superantigens book, molecular biology, biochemistry, and cellular biology, with a strong focus on disease models utilized to determine the role of superantigens in human disease.

Superantigens are unusual bacterial toxins that interact with exceedingly large numbers of T4-lymphocytes. They bind to the surface of the target cell but do not enter the cell. Figure \(\PageIndex{1}\): Binding of Peptide Epitopes from Exogenous Antigens to MHC-II Molecules. SUPERANTIGEN When the immune system encounters a conventional T-dependent antigen, only a small fraction of the T cell population is able to recognize the antigen and become activated.

However, some antigens can polyclonally. A comprehensive examination of these fascinating the basic molecular mechanisms of superantigen action, their structure and function, and their role in human diseases. Explains the clinical consequences of superantigen intoxication and the latest Price: $ Superantigens are microbial peptides that can polyclonally activate large portion of T cells.

Antigen Processing and Presentation Conventional protein antigens are processed by B cell and a peptide of the protein antigen is presented to its matching antigen-specific CD4 T cell via MHC-II-peptide:TCR. The book is organized into 5 sections with a total of 16 chapters.

The first section is an overview of the breadth and scope of superantigen research, including an up-to date catalog of superantigens characterized from both bacteria and viruses, their cellular interactions, and disease associations.

Since the discovery of viral superantigens inimmunologists have made a number of new discoveries. The discoveries, especially those relating to the interplay between the immune system and viruses producing superantigens, have had a great impact on immunology and virology, as it appears that some diseases are triggered or exacerbated by viral superantigens.

ISBN: OCLC Number: Description: viii, pages: illustrations. Contents: Molecular genetics of pyrogenic exotoxin "superantigens" of group A streptococci and staphylococcus aureus --T cell recognition of superantigens --T cell activation by superantigens --dependence on MHC class Ii molecules --The.

Superantigens stimulate T cells non-specifically without normal antigenic recognition (Figure ). Up to one in five T cells may be activated, whereas only 1 in 10, are stimulated during antigen presentation. Cytokines are released in large amounts, causing the symptoms of TSS.

Superantigens Author: Timothy Foster. Superantigens (SAgs) are proteins that cause the T-cells of the immune system to over-react to infection. They are produced by certain infectious bacteria and viruses. The immune system over-reaction to the antigen causes a group of diseases that manifest in fever and shock, such as food poisoning, toxic shock syndrome, and Kawasaki disease.

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Superantigens are typically exotoxins secreted by bacteria or endotoxins produced body cells after a viral infection. Food poisoning is often the result of superantigens as is toxic shock syndrome and scarlet fever. To learn more about the book this website supports, please visit its Information Center.

McGraw-Hill Higher Education Any. Superantigens are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. Superantigens are.

Superantigens are a rapidly growing new class of ligands for human B-cells. The study of their interaction with lymphocytes provides insight into important mechanisms of the immune system.

In this book, leading scientists survey the progress recently made in the identification, the nature, the Price: $ Superantigens (SAgs) are a class of antigens that result in excessive activation of the immune system.

Specifically it causes non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. SAgs are produced by some pathogenic viruses and bacteria most likely as a defense mechanism against the immune system. Superantigens have received a great deal of attention since the discovery of their mechanisms in Since then, a wealth of knowledge about their structure and molecular mechanisms has been presented, yet little information has been forthcoming on their direct role in diseases, other than the obvious food poisoning and toxic shock.

EENDOGENOUS SUPERANTIGENS NDOGENOUS SUPERANTIGENS Endogenous Superantigens (ESAgs) are cell membrane proteins encoded by certain viruses that infect mammalian cells.

[18] In humans ESAg is encoded by env gene of human endogenous retrovirus (HERV), and all humans carry numerous copies of HERV in their genome.

Exact significance of ESAg is not known. Superantigens also occur endogen­ ously in mice, most notably the enigmatic Mis determinants, that have withstood characterization for nearly 20 years. Only very recently was it found that Mis is probably encoded by endogenous retroviruses.

The list of candidates that are implicated as being superantigens. ISBN: OCLC Number: Description: 1 online resource (x, pages 13 illustrations) Contents: Molecular Genetics of Pyrogenic Exotoxin "Superantigens" of Group A Streptococci and Staphylococcus aureus --T Cell Recognition of Superantigens --T Cell Activation by Superantigens--Dependence on MHC Class II Molecules --The Human T Cell Response to Mitogenic.

ISBN: OCLC Number: Description: xii, pages: illustrations ; 24 cm. Contents: Superantigens: structure, function, and diversity / Matthew D. Baker --Expression, purification, and detection of novel streptococcal superantigens / John K.

McCormick --Flow cytometric detection of MMTV superantigens / Gary Winslow --Spectrophotometric methods for the. Book Description. This up-to-date sourcebook covers viral and bacterial superantigens (SAgs) from molecular structure and immunological processes to pathology.

Degradability Antigens that are easily phagocytosed are generally more immunogenic. This is because for most antigens (T-dependant antigens, see below) the development of an immune response requires that the antigen be phagocytosed, processed and presented.

Viral Superantigens is the first complete review of this new area of study. This comprehensive reference covers every aspect of viral superantigens and related subjects, including effects on the T cell repertoire and viral superantigen-mediated diseases.

Read the description of Streptococcus pyogenes and match the bacterium with the description of the organism and the infection it causes. Superantigens are unusual bacterial toxins that interact with exceedingly large numbers of T4-lymphocytes.

They bind to the surface of the target cell but do not enter the cell. Comprehensive and cutting-edge, Superantigen Protocols provides a broad range of novel immunological and biochemical techniques that can be successfully applied not only to the structural, functional, and clinical properties of superantigens, but also to the many varieties of.

Learn superantigens with free interactive flashcards. Choose from 21 different sets of superantigens flashcards on Quizlet. Superantigens are molecules, including endogenous retroviral gene products and microbial toxins, that share a unique set of characteristics.

They bind with high affinity to major histocompatibility complex class II at regions distinct from the conventional antigen binding groove and cause prolific activation or anergy of T cells with certain T Cited by: Bacterial superantigens (SAgs) are powerful T-cell stimulatory molecules produced primarily by Staphylococcus aureus and Streptococcus pyogenes.

Bacterial SAgs possess the unique ability to cross-link major histocompatibility complex (MHC) class II molecules and T-cell receptors, which in turn is responsible for their ability to illicit an immune response several orders of magnitude greater Cited by: Start studying Superantigen study guide #3.

Learn vocabulary, terms, and more with flashcards, games, and other study tools. Synopsis: Superantigens constitute a pdf family of bacterial and viral proteins that share the capacity pdf inducing massive activation of the immune system. This volume contains contributions from leaders in the field of classical T cell superantigens and sheds light on relevant B cell superantigens at the molecular and biochemical : $The term superantigen download pdf has been coined by Kappler and Marrack (1) as an operational definition of various T-cell activating substances with specificity for T cell antigen receptors comprising certain superantigen-specific means that many or all T cells expressing these Vβ respond to a superantigen, independent of their original antigen-specificity and MHC restriction: e.g.

the.Ebook Exam 4. STUDY. Flashcards. Learn. Write. Spell. Test. PLAY. Match. Gravity. Created by. ebook. Chapter Terms in this set (78) Antibodies are produced by.

plasma B cells. Superantigens are produced by. Staphylococcus aureus in toxic shock syndrome. Toxic shock syndrome is a mild disease similar to other mild allergic reactions.